Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215068 | 1.00 | MET (0.64) | METKCNH2JAK2SLC6A4HTR2C | |
| SCHEMBL488307 | 1.00 | MET (0.64) | METKCNH2JAK2SLC6A4HTR2C | |
| SCHEMBL10381874 | 0.91 | MET (0.53) | METKCNH2JAK2SLC6A4HTR2C | |
| SCHEMBL13455023 | 0.89 | MET (0.65) | METKCNH2JAK2CCNCCDK8 | |
| SCHEMBL488408 | 0.86 | MET (0.76) | METKCNH2JAK2SLC6A4HTR2B | |
| SCHEMBL30454187 | 0.86 | MET (0.76) | METKCNH2JAK2SLC6A4HTR2B | |
| SCHEMBL13010719 | 0.86 | MET (0.47) | METKCNH2JAK2SLC6A4HTR2C | |
| SCHEMBL30454349 | 0.85 | MET (0.65) | METKCNH2JAK2 | |
| SCHEMBL488583 | 0.85 | MET (0.65) | METKCNH2JAK2 | |
| SCHEMBL10215074 | 0.85 | MET (0.65) | METKCNH2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |