SCHEMBL30453676

SCHEMBL30453676

CC(Oc1cc(-c2ccc(NS(=O)(=O)CCN3CC[C@@H](O)C3)cc2)cnc1N)c1c(F)ccc(F)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MET P08581 13/20 0.54
ALK Q9UM73 7/20 0.46
AXL P30530 1/20 0.46
JAK2 O60674 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487634 1.00 MET (0.54) METALKAXLJAK2
SCHEMBL10215537 0.96 MET (0.60) METALKAXLJAK2
SCHEMBL30453823 0.96 MET (0.60) METALKAXLJAK2
SCHEMBL488437 0.96 MET (0.57) METALKAXLJAK2
SCHEMBL30453689 0.96 MET (0.57) METALKAXLJAK2
SCHEMBL488647 0.92 MET (0.63) METALKAXLJAK2
SCHEMBL30453141 0.92 MET (0.63) METALKAXLJAK2
SCHEMBL30453055 0.88 MET (0.64) METALKAXLJAK2
SCHEMBL488043 0.88 MET (0.64) METALKAXLJAK2
SCHEMBL488174 0.87 MET (0.47) METJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4599890-A2 SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS Kyoto University (JP) 2025-08-13 EP disclosed
CN-113181362-B Medicament for preventing and/or treating amyotrophic lateral sclerosis 国立大学法人京都大学 2023-06-13 CN disclosed