Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 14/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488144 | 1.00 | ALK (0.55) | ALKROS1METJAK2 | |
| SCHEMBL30453389 | 0.95 | MET (0.62) | ALKROS1METJAK2 | |
| SCHEMBL487523 | 0.95 | MET (0.62) | ALKROS1METJAK2 | |
| SCHEMBL30453267 | 0.92 | MET (0.53) | ALKROS1METJAK2 | |
| SCHEMBL487871 | 0.92 | MET (0.53) | ALKROS1METJAK2 | |
| SCHEMBL30453619 | 0.87 | MET (0.60) | ALKROS1METJAK2 | |
| SCHEMBL487863 | 0.87 | MET (0.60) | ALKROS1METJAK2 | |
| SCHEMBL488245 | 0.86 | MET (0.62) | ALKMETJAK2 | |
| SCHEMBL487999 | 0.86 | MET (0.62) | ALKMETJAK2 | |
| SCHEMBL30453218 | 0.85 | MET (0.52) | ALKROS1METJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |