Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487934 | 1.00 | MET (0.54) | METFYNAXLMERTKNPC1 | |
| SCHEMBL487853 | 0.91 | MET (0.64) | METKCNH2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL30454525 | 0.91 | MET (0.64) | METKCNH2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL30453422 | 0.89 | MET (0.57) | METFYNAXLMERTKNTRK1 | |
| SCHEMBL487685 | 0.89 | MET (0.57) | METFYNAXLMERTKNTRK1 | |
| SCHEMBL30452813 | 0.86 | MET (0.58) | METAXLMERTKATRBMPR1B | |
| SCHEMBL488047 | 0.86 | MET (0.58) | METAXLMERTKATRBMPR1B | |
| SCHEMBL487971 | 0.86 | MET (0.56) | METAXLMERTKKCNH2BMPR1B | |
| SCHEMBL488222 | 0.86 | MET (0.58) | METFYNAXLMERTKNPC1 | |
| SCHEMBL10215391 | 0.86 | MET (0.58) | METFYNAXLMERTKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |