Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 13/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243885 | 0.82 | SCD (0.65) | SCDNPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL244826 | 0.81 | SCD (0.64) | SCDNPC1ALDH1A1RAB9A | |
| SCHEMBL3051532 | 0.81 | SCD (0.64) | SCDNPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3585867 | 0.80 | NPC1 (0.77) | SCDNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL3586148 | 0.80 | SCD (0.73) | SCDNPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3585303 | 0.79 | SCD (0.61) | SCDNPC1HPGDRAB9A | |
| SCHEMBL3046765 | 0.79 | SCD (0.61) | SCDNPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3052998 | 0.79 | SCD (0.61) | SCDNPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5360056 | 0.79 | SCD (0.58) | SCDNPC1HPGD | |
| SCHEMBL3583154 | 0.77 | SCD (0.76) | SCDNPC1HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258160-B2 | SCD1 inhibitors triazole and tetrazole compounds | NOVARTIS AG (CH) | 2012-09-04 | — | — | US | disclosed |
| US-8258160-B2 | SCD1 inhibitors triazole and tetrazole compounds | NOVARTIS AG (CH) | 2012-09-04 | — | — | US | disclosed |
| US-20100029722-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
| US-20100029722-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029722-A1 | ORGANIC COMPOUNDS | SCD, SCD5, FADS2 | SCD 1/4885NPC1 228/4885HPGD 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.