Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317365 | 1.00 | DHFR (0.66) | DHFRADORA1ADORA2AGFERKMT2A | |
| Hydrochloric Acid SCHEMBL12813248 | 0.98 | DHFR (0.64) | DHFRADORA1ADORA2AGFERKMT2A | |
| Hydrochloric Acid SCHEMBL1091696 | 0.98 | DHFR (0.64) | DHFRADORA1ADORA2AGFERKMT2A | |
| SCHEMBL27613072 | 0.90 | DHFR (0.59) | DHFRADORA1ADORA2AGFERKMT2A | |
| SCHEMBL27631899 | 0.87 | DHFR (0.69) | DHFRADORA1ADORA2A | |
| SCHEMBL9435242 | 0.84 | DHFR (0.62) | DHFRADORA1ADORA2AKMT2A | |
| SCHEMBL29116207 | 0.83 | DHFR (0.61) | DHFRADORA1ADORA2AKMT2A | |
| SCHEMBL31612551 | 0.83 | DHFR (0.61) | DHFRADORA1ADORA2AKMT2A | |
| SCHEMBL8137827 | 0.82 | FGFR1 (0.63) | DHFRADORA1ADORA2AGFERKMT2A | |
| SCHEMBL4582424 | 0.82 | ADORA1 (0.83) | ADORA1ADORA2AGFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486348-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023166153-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC (US) | 2023-09-07 | — | — | WO | disclosed |
| CN-113061116-B | Aminopyrimidine compound, preparation method, composition and application thereof | 上海医药工业研究院 | 2023-07-25 | — | — | CN | disclosed |
| CN-113227072-B | 2, 4-diaminopyrimidine derivatives and uses thereof | 上海喆邺生物科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |