Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.67 |
| ▸ | JAK2 | O60674 | 7/20 | 0.43 |
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | TYK2 | P29597 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488376 | 1.00 | MET (0.67) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL10270841 | 0.88 | MET (0.66) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL30453289 | 0.88 | MET (0.66) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL488357 | 0.88 | MET (0.66) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL10215074 | 0.86 | MET (0.65) | METJAK2KCNH2 | |
| SCHEMBL488583 | 0.86 | MET (0.65) | METJAK2KCNH2 | |
| SCHEMBL30454349 | 0.86 | MET (0.65) | METJAK2KCNH2 | |
| SCHEMBL10215079 | 0.85 | MET (0.66) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL10270463 | 0.85 | MET (0.66) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL5496122 | 0.84 | MET (0.65) | METJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |