Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.57 |
| ▸ | JAK2 | O60674 | 5/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488579 | 1.00 | MET (0.57) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL30454123 | 1.00 | MET (0.57) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL488387 | 1.00 | MET (0.57) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL488346 | 1.00 | MET (0.57) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL30454118 | 0.92 | MET (0.66) | METJAK2ALK | |
| SCHEMBL488823 | 0.92 | MET (0.66) | METJAK2ALK | |
| SCHEMBL487967 | 0.92 | MET (0.66) | METJAK2ALK | |
| SCHEMBL30454202 | 0.92 | MET (0.66) | METJAK2ALK | |
| SCHEMBL487965 | 0.92 | MET (0.66) | METJAK2ALK | |
| SCHEMBL487824 | 0.91 | MET (0.67) | METJAK2ALKJAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |