Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.76 |
| ▸ | JAK2 | O60674 | 2/20 | 0.71 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.66 |
| ▸ | ROS1 | P08922 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488400 | 1.00 | MET (0.76) | METJAK2ALKROS1 | |
| SCHEMBL488592 | 0.91 | MET (0.78) | METJAK2ALK | |
| SCHEMBL30454160 | 0.91 | MET (0.78) | METJAK2ALK | |
| SCHEMBL30453067 | 0.89 | MET (0.84) | METJAK2ALK | |
| SCHEMBL30453476 | 0.89 | MET (0.84) | METJAK2ALK | |
| SCHEMBL488641 | 0.89 | MET (0.84) | METJAK2ALK | |
| SCHEMBL488237 | 0.89 | MET (0.84) | METJAK2ALK | |
| SCHEMBL30453848 | 0.89 | MET (0.74) | METJAK2ALK | |
| SCHEMBL488151 | 0.89 | MET (0.74) | METJAK2ALK | |
| SCHEMBL488632 | 0.88 | MET (0.94) | METJAK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |