Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488530 | 1.00 | CD274 (0.52) | CD274METNAMPTTSHRWDR5 | |
| SCHEMBL488424 | 0.95 | CD274 (0.58) | CD274MET | |
| SCHEMBL30453287 | 0.95 | CD274 (0.58) | CD274MET | |
| SCHEMBL30453420 | 0.93 | MET (0.55) | CD274MET | |
| SCHEMBL488220 | 0.93 | MET (0.55) | CD274MET | |
| SCHEMBL30454410 | 0.91 | MET (0.55) | CD274METCYP2D6CYP2C9 | |
| SCHEMBL488059 | 0.91 | MET (0.55) | CD274METCYP2D6CYP2C9 | |
| SCHEMBL10316748 | 0.89 | MET (0.51) | CD274METNAMPTTSHRWDR5 | |
| SCHEMBL487659 | 0.88 | MET (0.56) | CD274MET | |
| SCHEMBL30452636 | 0.88 | MET (0.56) | CD274MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |