Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454569 | 0.93 | GLP1R (0.50) | GLP1R | |
| SCHEMBL30453956 | 0.91 | GLP1R (0.55) | GLP1RCYP2C8KCNH2HTR1A | |
| SCHEMBL30454376 | 0.83 | GLP1R (0.34) | GLP1RHTR1A | |
| SCHEMBL29559346 | 0.81 | GLP1R (0.41) | GLP1RCYP2C8KCNH2HTR1A | |
| SCHEMBL30455033 | 0.81 | GLP1R (0.42) | GLP1R | |
| SCHEMBL29559363 | 0.79 | GLP1R (0.39) | GLP1RCYP2C8KCNH2HTR1A | |
| SCHEMBL30454330 | 0.78 | DRD4 (0.37) | KCNH2HTR1A | |
| SCHEMBL30284281 | 0.77 | GLP1R (0.39) | GLP1R | |
| SCHEMBL30200446 | 0.75 | DRD4 (0.36) | GLP1R | |
| SCHEMBL22391889 | 0.75 | GLP1R (0.77) | GLP1RCYP2C8KCNH2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |