SCHEMBL30454569

SCHEMBL30454569

Fc1cc(Cl)ccc1COc1cccc(C2=CCN(CC3C=CC=CC3CC3CCO3)CC2)n1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30454077 0.93 GLP1R (0.49) GLP1R
SCHEMBL30453956 0.89 GLP1R (0.55) GLP1R
SCHEMBL30455033 0.88 GLP1R (0.42) GLP1R
SCHEMBL30284281 0.85 GLP1R (0.39) GLP1R
SCHEMBL30454376 0.85 GLP1R (0.34) GLP1R
SCHEMBL30454984 0.81 GLP1R (0.47) GLP1R
SCHEMBL30454558 0.80 GLP1R (0.51) GLP1R
SCHEMBL30646812 0.80 GLP1R (0.45) GLP1R
SCHEMBL30646852 0.80 GLP1R (0.45) GLP1R
SCHEMBL30021596 0.79 GLP1R (0.44) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227068-B GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2023-06-13 — — CN disclosed
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