Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.62 |
| ▸ | ATR | Q13535 | 7/20 | 0.51 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487914 | 1.00 | MET (0.62) | METATRMAP4K3HRH3MAP4K4 | |
| SCHEMBL30453497 | 0.91 | MET (0.62) | METATRHRH3 | |
| SCHEMBL488305 | 0.91 | MET (0.62) | METATRHRH3 | |
| SCHEMBL30454114 | 0.91 | MET (0.61) | METATRHRH3 | |
| SCHEMBL30453385 | 0.91 | MET (0.61) | METATRHRH3 | |
| SCHEMBL488164 | 0.91 | MET (0.61) | METATRHRH3 | |
| SCHEMBL487911 | 0.91 | MET (0.61) | METATRHRH3 | |
| SCHEMBL487661 | 0.90 | MET (0.54) | METATRMAP4K4 | |
| SCHEMBL30453159 | 0.90 | MET (0.54) | METATRMAP4K4 | |
| SCHEMBL487895 | 0.89 | MET (0.64) | METATRMAP4K3HRH3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |