Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814471 | 1.00 | JAK2 (0.37) | JAK2GRM5MAPTALDH1A1GAA | |
| SCHEMBL2596436 | 0.89 | MAPT (0.40) | GRM5MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL29659230 | 0.89 | MAPT (0.40) | GRM5MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL6264453 | 0.79 | UHRF1 (0.41) | JAK2GRM5MAPTALDH1A1GAA | |
| SCHEMBL18053842 | 0.79 | JAK2 (0.37) | JAK2GRM5MAPTALDH1A1GAA | |
| SCHEMBL21281617 | 0.79 | JAK2 (0.35) | JAK2MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL6261287 | 0.73 | ITGAV (0.37) | JAK2 | |
| SCHEMBL6261283 | 0.73 | JAK2 (0.34) | JAK2MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL13212813 | 0.71 | ALDH1A1 (0.40) | GRM5MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL2848871 | 0.71 | GRM5 (0.41) | JAK2GRM5LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |