Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.67 |
| ▸ | MET | P08581 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488652 | 1.00 | CSF1R (0.67) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL488005 | 0.91 | CSF1R (0.66) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL30453813 | 0.91 | CSF1R (0.66) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL488037 | 0.86 | CSF1R (0.61) | CSF1RMETKDM4ECHEK2 | |
| SCHEMBL30453931 | 0.86 | CSF1R (0.61) | CSF1RMETKDM4ECHEK2 | |
| SCHEMBL27630163 | 0.81 | CSF1R (0.60) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL5484077 | 0.81 | CSF1R (0.47) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL488752 | 0.79 | CSF1R (0.57) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL29507219 | 0.79 | CSF1R (0.57) | CSF1RMETSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL488575 | 0.78 | CSF1R (0.56) | CSF1RMETSMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |