Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.61 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488037 | 1.00 | CSF1R (0.61) | CSF1RATRMAP4K4METLDHA | |
| SCHEMBL30453813 | 0.87 | CSF1R (0.66) | CSF1RATRMETCHEK2KDM4E | |
| SCHEMBL488005 | 0.87 | CSF1R (0.66) | CSF1RATRMETCHEK2KDM4E | |
| SCHEMBL30454422 | 0.86 | CSF1R (0.67) | CSF1RMETCHEK2KDM4E | |
| SCHEMBL488652 | 0.86 | CSF1R (0.67) | CSF1RMETCHEK2KDM4E | |
| SCHEMBL30454721 | 0.84 | CSF1R (0.45) | CSF1RATRMAP4K4METLDHA | |
| SCHEMBL488449 | 0.84 | CSF1R (0.45) | CSF1RATRMAP4K4METLDHA | |
| SCHEMBL10381288 | 0.80 | NEK2 (0.43) | CSF1RATRMAP4K4METLDHA | |
| SCHEMBL15542410 | 0.80 | LDHB (0.61) | CSF1RATRMAP4K4LDHALDHB | |
| SCHEMBL488702 | 0.79 | MET (0.60) | CSF1RATRMAP4K4METLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |