Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.51 |
| ▸ | ATR | Q13535 | 2/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488235 | 1.00 | MET (0.59) | METMAP4K4ATRERN1IKBKB | |
| SCHEMBL488053 | 0.95 | MET (0.55) | METMAP4K4ATRFYNKDR | |
| SCHEMBL30454113 | 0.95 | MET (0.55) | METMAP4K4ATRFYNKDR | |
| SCHEMBL30454809 | 0.93 | MAP4K4 (0.53) | METMAP4K4ERN1KDRGRK5 | |
| SCHEMBL488204 | 0.93 | MAP4K4 (0.53) | METMAP4K4ERN1KDRGRK5 | |
| SCHEMBL488490 | 0.92 | MET (0.52) | METMAP4K4ATRFYNGRK5 | |
| SCHEMBL30453942 | 0.91 | MET (0.70) | METATR | |
| SCHEMBL487903 | 0.91 | MET (0.70) | METATR | |
| SCHEMBL487728 | 0.89 | MET (0.49) | METMAP4K4KDRGRK5PIK3CD | |
| SCHEMBL30453447 | 0.89 | MET (0.49) | METMAP4K4KDRGRK5PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |