Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 15/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | NPM1 | P06748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488303 | 1.00 | MAP4K3 (0.47) | MAP4K3METCHEK2SGK1ALK | |
| SCHEMBL30453976 | 0.89 | MAP4K3 (0.46) | MAP4K3METCHEK2SGK1ALK | |
| SCHEMBL488492 | 0.89 | MAP4K3 (0.46) | MAP4K3METCHEK2SGK1ALK | |
| SCHEMBL30453613 | 0.86 | MET (0.45) | MAP4K3METCHEK2SGK1ALK | |
| SCHEMBL488524 | 0.86 | MET (0.45) | MAP4K3METCHEK2SGK1ALK | |
| SCHEMBL30453218 | 0.85 | MET (0.52) | MAP4K3METALKINSRNPM1 | |
| SCHEMBL487676 | 0.85 | MET (0.52) | MAP4K3METALKINSRNPM1 | |
| SCHEMBL488603 | 0.85 | MET (0.51) | MAP4K3METCHEK2ALK | |
| SCHEMBL30453827 | 0.85 | MET (0.51) | MAP4K3METCHEK2ALK | |
| SCHEMBL487733 | 0.84 | MET (0.50) | MAP4K3METCHEK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |