Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.48 |
| ▸ | EGLN3 | Q9H6Z9 | 6/20 | 0.48 |
| ▸ | FLT1 | P17948 | 4/20 | 0.48 |
| ▸ | VEGFA | P15692 | 4/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257501 | 1.00 | EGLN1 (0.48) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL24257795 | 0.88 | EGLN1 (0.41) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL30452729 | 0.88 | EGLN1 (0.41) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL24257637 | 0.87 | EGLN1 (0.50) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL24257567 | 0.86 | EGLN1 (0.65) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL30546834 | 0.84 | EGLN1 (0.56) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL30452349 | 0.84 | AKR1C3 (0.42) | — | |
| SCHEMBL24257500 | 0.84 | AKR1C3 (0.42) | — | |
| SCHEMBL24257601 | 0.84 | EGLN1 (0.56) | EGLN1EGLN3FLT1VEGFAFTO | |
| SCHEMBL24257636 | 0.83 | EGLN1 (0.51) | EGLN1EGLN3FLT1VEGFAFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |