Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.64 |
| ▸ | MET | P08581 | 14/20 | 0.64 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.64 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.64 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.64 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.64 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.64 |
| ▸ | AXL | P30530 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488153 | 1.00 | ALK (0.64) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL488650 | 0.95 | ALK (0.57) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL30453113 | 0.95 | ALK (0.57) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL10215655 | 0.88 | MET (0.65) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL10215653 | 0.88 | MET (0.65) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL487856 | 0.88 | MET (0.65) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL30454989 | 0.88 | MET (0.65) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL487918 | 0.88 | MET (0.65) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL30453258 | 0.88 | MET (0.65) | ALKMETMAP4K2MAP3K1AAK1 | |
| SCHEMBL30452512 | 0.88 | MET (0.78) | ALKMETMAP4K2MAP3K1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |