Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.57 |
| ▸ | MET | P08581 | 5/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488389 | 1.00 | ATR (0.57) | ATRMETCHEK2L3MBTL3L3MBTL1 | |
| SCHEMBL30453101 | 0.93 | MET (0.60) | ATRMETCHEK2L3MBTL3L3MBTL1 | |
| SCHEMBL488665 | 0.93 | MET (0.60) | ATRMETCHEK2L3MBTL3L3MBTL1 | |
| SCHEMBL488521 | 0.92 | MET (0.68) | ATRMETCHEK2MAP4K3 | |
| SCHEMBL488679 | 0.90 | MET (0.61) | ATRMETCHEK2L3MBTL3L3MBTL1 | |
| SCHEMBL488713 | 0.87 | MET (0.50) | ATRMETCHEK2MAP4K3 | |
| SCHEMBL10216401 | 0.87 | MET (0.50) | ATRMETCHEK2MAP4K3 | |
| SCHEMBL30453644 | 0.87 | MET (0.50) | ATRMETCHEK2MAP4K3 | |
| SCHEMBL488710 | 0.87 | MET (0.50) | ATRMETCHEK2MAP4K3 | |
| SCHEMBL489049 | 0.87 | ATR (0.55) | ATRMETCHEK2L3MBTL1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |