Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 19/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802481 | 0.83 | GRIN2B (0.43) | GRIN2B | |
| SCHEMBL11160938 | 0.80 | CSNK2A2 (0.42) | NPC1 | |
| SCHEMBL23697918 | 0.75 | KDM4E (0.43) | KMT2A | |
| SCHEMBL2116411 | 0.74 | HSD17B10 (0.34) | — | |
| SCHEMBL24802532 | 0.74 | NPC1 (0.60) | GRIN2BNPC1RAB9AKMT2A | |
| SCHEMBL10733734 | 0.73 | SMN1; SMN2 (0.48) | GRIN2BNPC1RAB9AKMT2A | |
| SCHEMBL17605207 | 0.72 | CCNC (0.47) | — | |
| SCHEMBL25419023 | 0.71 | HSD17B10 (0.36) | NPC1RAB9A | |
| SCHEMBL4892136 | 0.71 | LMNA (0.35) | — | |
| SCHEMBL21611159 | 0.71 | GRIN2B (0.67) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |