Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.66 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488802 | 1.00 | MET (0.66) | METALKCHEK2MAP4K3CD274 | |
| SCHEMBL30454107 | 0.96 | MET (0.59) | METALKCHEK2CD274HPGDS | |
| SCHEMBL488600 | 0.96 | MET (0.59) | METALKCHEK2CD274HPGDS | |
| SCHEMBL487974 | 0.92 | MET (0.60) | METALKCHEK2MAP4K3 | |
| SCHEMBL30452825 | 0.92 | MET (0.60) | METALKCHEK2MAP4K3 | |
| SCHEMBL30453551 | 0.92 | MET (0.59) | METALKMAP4K3CD274ALDH1A1 | |
| SCHEMBL488919 | 0.92 | MET (0.59) | METALKMAP4K3CD274ALDH1A1 | |
| SCHEMBL488251 | 0.92 | MET (0.59) | METALKMAP4K3 | |
| SCHEMBL30452830 | 0.92 | MET (0.59) | METALKMAP4K3 | |
| SCHEMBL488149 | 0.90 | MET (0.60) | METCHEK2CD274HPGDSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |