Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27157383 | 0.81 | MCL1 (0.45) | MCL1PTGER4ALDH1A1KDM4ELMNA | |
| SCHEMBL28312615 | 0.81 | KDM4E (0.50) | MCL1ALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL23361781 | 0.77 | FGFR1 (0.47) | PTGER4KDM4CPLA2G4AGRIN2B | |
| SCHEMBL29393184 | 0.77 | FGFR1 (0.47) | PTGER4KDM4CPLA2G4AGRIN2B | |
| SCHEMBL30548170 | 0.77 | FGFR1 (0.47) | PTGER4KDM4CPLA2G4AGRIN2B | |
| SCHEMBL20268541 | 0.77 | FGFR1 (0.47) | PTGER4KDM4CPLA2G4AGRIN2B | |
| Ammonia Solution, Strong SCHEMBL30676125 | 0.76 | FGFR1 (0.46) | PTGER4KDM4CPLA2G4AGRIN2B | |
| SCHEMBL31140564 | 0.75 | PTGER4 (0.48) | PTGER4 | |
| SCHEMBL28586562 | 0.75 | CNR2 (0.46) | PLA2G4AEPHX2 | |
| SCHEMBL28246496 | 0.75 | MCL1 (0.54) | MCL1ALDH1A1KDM4ELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242067-B | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-117242067-A | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |