Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 17/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140527 | 0.90 | PTGER4 (0.58) | PTGER4 | |
| SCHEMBL29770328 | 0.89 | PTGER4 (0.52) | PTGER4GLP1RACSS2 | |
| SCHEMBL23980750 | 0.89 | PTGER4 (0.52) | PTGER4GLP1RACSS2 | |
| SCHEMBL30497392 | 0.88 | GLP1R (0.49) | PTGER4GLP1R | |
| SCHEMBL29149774 | 0.86 | GLP1R (0.50) | GLP1R | |
| SCHEMBL29149777 | 0.86 | GLP1R (0.50) | GLP1R | |
| SCHEMBL20266409 | 0.85 | GLP1R (0.50) | GLP1R | |
| SCHEMBL24529616 | 0.85 | GLP1R (0.51) | PTGER4GLP1R | |
| SCHEMBL20266411 | 0.85 | GLP1R (0.50) | GLP1R | |
| SCHEMBL24338858 | 0.85 | GLP1R (0.50) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568664-A1 | COMBINATION COMPRISING A THR-BETA AGONIST AND A GLP-1R AGONIST FOR USE IN TREATING A LIVER DISORDER OR A CARDIOMETABOLIC DISEASE | Terns Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024211898-A1 | COMBINATION COMPRISING A THRBETA AGONIST ANDA GLP-1R AGONIST FOR USE IN TREATING A LIVER DISORDER OR A CARDIOMETABOLIC DISEASE | TERNS PHARMACEUTICALS, INC. (US) | 2024-10-10 | — | — | WO | disclosed |