Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455741 | 1.00 | NAMPT (0.44) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL18518436 | 0.87 | FFAR1 (0.53) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16977978 | 0.87 | FFAR1 (0.53) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL18518580 | 0.87 | FFAR1 (0.53) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL440450 | 0.87 | FFAR1 (0.53) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL439861 | 0.83 | NAMPT (0.45) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16977977 | 0.83 | NAMPT (0.45) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15805103 | 0.80 | NAMPT (0.41) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15799018 | 0.80 | NAMPT (0.41) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15799019 | 0.80 | NAMPT (0.41) | NAMPTCYP3A4ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11905284-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | PFIZER INC. (US) | 2024-02-20 | — | — | US | disclosed |
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | NAMPT 1268/4885CYP3A4 79/4885ALDH1A1 754/4885 |
| US-11905284-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | CHRM1, CHRM5, CHRM2 | NAMPT 1268/4885CYP3A4 79/4885ALDH1A1 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.