Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247787 | 0.82 | DAO (0.54) | DAOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23621836 | 0.78 | DDB1 (0.45) | DAOPOLBPDE10ADDB1CRBN | |
| SCHEMBL21385026 | 0.78 | DAO (0.52) | DAOPOLBDDB1CRBNDTYMK | |
| SCHEMBL29038509 | 0.78 | DAO (0.63) | DAOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15157018 | 0.78 | DAO (0.49) | DAOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2248725 | 0.78 | CCR5 (0.52) | POLBPDE10ADDB1CRBNGPR119 | |
| SCHEMBL2256797 | 0.77 | DAO (0.47) | DAOPOLB | |
| SCHEMBL481847 | 0.76 | MEN1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8199344 | 0.76 | MEN1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23253173 | 0.76 | POLB (0.45) | DAOPOLBPDE10ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478211-B | Novel CGRP receptor antagonist and application thereof | 石家庄迪斯凯威医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116478211-A | Novel CGRP receptor antagonist and application thereof | 石家庄迪斯凯威医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |