Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25707245 | 1.00 | BRD4 (0.34) | BRD4CREBBPFGFR1IDO1 | |
| SCHEMBL29282600 | 1.00 | BRD4 (0.34) | BRD4CREBBPFGFR1IDO1 | |
| SCHEMBL29282589 | 0.90 | BRD4 (0.37) | BRD4CREBBPFGFR1IDO1 | |
| SCHEMBL25707208 | 0.90 | BRD4 (0.37) | BRD4CREBBPFGFR1IDO1 | |
| SCHEMBL30166775 | 0.90 | BRD4 (0.37) | BRD4CREBBPFGFR1IDO1 | |
| SCHEMBL24815411 | 0.90 | BRD4 (0.37) | BRD4CREBBPFGFR1IDO1 | |
| SCHEMBL26833793 | 0.88 | BRD4 (0.34) | BRD4CREBBP | |
| SCHEMBL24816665 | 0.88 | BRD4 (0.34) | BRD4CREBBP | |
| SCHEMBL30166841 | 0.88 | BRD4 (0.34) | BRD4CREBBP | |
| SCHEMBL24814384 | 0.84 | BRD4 (0.33) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163031-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2025-05-22 | — | — | US | disclosed |
| CN-118019737-A | Beta-lactam derivatives for the treatment of diseases | 英矽智能科技知识产权有限公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20230192667-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192667-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | QPCT, QPCTL, BCAT1 | BRD4 1268/4885CREBBP 620/4885FGFR1 3239/4885 |
| US-20250163031-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | QPCT, QPCTL, BCAT1 | BRD4 1268/4885CREBBP 620/4885FGFR1 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.