Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.65 |
| ▸ | MTOR | P42345 | 8/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230973 | 1.00 | PIK3CA (0.65) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL25223744 | 0.89 | PIK3CA (0.67) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL30456388 | 0.89 | PIK3CA (0.67) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL25227969 | 0.88 | PIK3CA (0.58) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL25224496 | 0.81 | PIK3CA (0.67) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL258574 | 0.79 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL25276720 | 0.77 | PIK3CA (0.86) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL25275051 | 0.77 | PIK3CA (0.66) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL25230093 | 0.77 | TRPM8 (0.67) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL16919706 | 0.75 | PIK3CA (0.66) | PIK3CAPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444289-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107592-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |