Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156197 | 1.00 | ALDH1A1 (0.41) | ALDH1A1NPSR1MAPTCHRM1HSD17B10 | |
| SCHEMBL1641646 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NPSR1MAPTCHRM1LMNA | |
| SCHEMBL1207411 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPSR1MAPTCHRM1LMNA | |
| SCHEMBL31028737 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPSR1MAPTCHRM1LMNA | |
| SCHEMBL31028797 | 0.82 | ALDH1A1 (0.38) | ALDH1A1NPSR1MAPTHSD17B10TDP1 | |
| SCHEMBL16586176 | 0.79 | ALDH1A1 (0.49) | ALDH1A1NPSR1MAPTLMNAHTT | |
| SCHEMBL1459863 | 0.79 | ALDH1A1 (0.49) | ALDH1A1NPSR1MAPTCHRM1HSD17B10 | |
| SCHEMBL958949 | 0.79 | ALDH1A1 (0.56) | ALDH1A1NPSR1MAPTHSD17B10TDP1 | |
| SCHEMBL31018073 | 0.79 | ALDH1A1 (0.56) | ALDH1A1NPSR1MAPTHSD17B10TDP1 | |
| SCHEMBL2066547 | 0.77 | HTT (0.53) | ALDH1A1MAPTHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | CHRM5, CHRM1, CHRM2 | ALDH1A1 622/4885NPSR1 32/4885MAPT 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.