Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327487 | 1.00 | TOP2A (0.42) | TOP2ACYP19A1TERTALDH1A1ALDH2 | |
| SCHEMBL21933120 | 1.00 | TOP2A (0.42) | TOP2ACYP19A1TERTALDH1A1ALDH2 | |
| SCHEMBL7920992 | 0.84 | HCRTR2 (0.45) | TOP2ACYP19A1ALDH1A1CA2HCRTR2 | |
| SCHEMBL21933121 | 0.81 | ADRA2A (0.41) | CYP19A1TERTALDH1A1ALDH2CHRNB2 | |
| SCHEMBL13630579 | 0.81 | ADRA2A (0.41) | CYP19A1TERTALDH1A1ALDH2CHRNB2 | |
| SCHEMBL13616553 | 0.81 | ADRA2A (0.41) | CYP19A1TERTALDH1A1ALDH2CHRNB2 | |
| SCHEMBL5536383 | 0.78 | MAP3K14 (0.42) | CYP19A1TERTALDH1A1ALDH2CA2 | |
| SCHEMBL22867760 | 0.78 | CYP19A1 (0.41) | CYP19A1TERTALDH1A1ALDH2CA2 | |
| SCHEMBL5536375 | 0.78 | CYP19A1 (0.47) | CYP19A1TERTALDH1A1ALDH2CA2 | |
| SCHEMBL10159264 | 0.78 | MAP3K14 (0.50) | TOP2ACYP19A1HCRTR2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | CHRM5, CHRM1, CHRM2 | TOP2A 4268/4885CYP19A1 2926/4885TERT 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.