Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | TPO | P07202 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239242 | 1.00 | DGAT1 (0.40) | DGAT1MPOTPOKCNH2NPC1 | |
| SCHEMBL21678682 | 1.00 | DGAT1 (0.40) | DGAT1MPOTPOKCNH2NPC1 | |
| SCHEMBL30457445 | 0.88 | DGAT1 (0.42) | DGAT1NPC1 | |
| SCHEMBL14158745 | 0.88 | DGAT1 (0.42) | DGAT1NPC1 | |
| SCHEMBL29854683 | 0.86 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL2693867 | 0.86 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL2238008 | 0.85 | DGAT1 (0.35) | DGAT1MAPT | |
| SCHEMBL30295772 | 0.85 | DGAT1 (0.35) | DGAT1MAPT | |
| SCHEMBL21632538 | 0.85 | DGAT1 (0.45) | DGAT1NPC1 | |
| SCHEMBL2696013 | 0.84 | DGAT1 (0.35) | DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080779-A | Pyrrolopyrimidine ITK inhibitors | 阿克拉瑞斯治疗股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-112823005-B | Pyrrolopyrimidine ITK inhibitors | 阿克拉瑞斯治疗股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023110843-A1 | HETEROBICYCLIC DERIVATIVES AS ITK INHIBITORS | ALMIRALL, S.A. (ES) | 2023-06-22 | — | — | WO | disclosed |