Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821087 | 1.00 | S1PR1 (0.41) | S1PR1ABL1METSLC6A2SLC6A4 | |
| SCHEMBL1506620 | 0.84 | S1PR1 (0.46) | S1PR1ABL1 | |
| SCHEMBL27810411 | 0.83 | SLC6A2 (0.46) | S1PR1SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL4458063 | 0.82 | AHR (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL15921608 | 0.81 | UGT2B7 (0.44) | S1PR1ABL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16950968 | 0.81 | S1PR1 (0.41) | S1PR1ABL1METSLC6A2SLC6A4 | |
| SCHEMBL28623523 | 0.80 | TRPV4 (0.46) | S1PR1ABL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10831235 | 0.79 | POLB (0.32) | S1PR1 | |
| SCHEMBL19198361 | 0.79 | S1PR1 (0.37) | S1PR1ABL1METSLC6A2SLC6A4 | |
| SCHEMBL27868723 | 0.77 | APP (0.41) | S1PR1SLC6A2SLC6A4SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |