SCHEMBL30457936

SCHEMBL30457936

CC(=O)Nc1ccn(C(=O)N2CCN(Cc3cc(Cl)cc(Oc4ccc(Cl)cc4)c3)CC2)n1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.71
MGLL Q99685 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20572217 1.00 FAAH (0.71) FAAHMGLL
SCHEMBL21821184 0.89 FAAH (0.53) FAAHMGLL
SCHEMBL25829846 0.86 FAAH (0.84) FAAHMGLL
SCHEMBL24971338 0.86 FAAH (0.78) FAAHMGLL
SCHEMBL30302097 0.83 FAAH (1.00) FAAHMGLL
SCHEMBL20566600 0.83 FAAH (1.00) FAAHMGLL
SCHEMBL21821041 0.81 FAAH (0.60) FAAHMGLL
SCHEMBL30302113 0.81 FAAH (0.77) FAAHMGLL
SCHEMBL20567055 0.81 FAAH (0.77) FAAHMGLL
SCHEMBL21287956 0.81 FAAH (0.47) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110678177-B Pyrazole MAGL inhibitors H.隆德贝克有限公司 2023-06-13 CN disclosed