Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234075 | 1.00 | HTT (0.50) | HTTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL31120903 | 0.80 | NPC1 (0.71) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2970236 | 0.80 | NPC1 (0.71) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31398710 | 0.80 | HDAC1 (0.51) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1121389 | 0.78 | NPC1 (0.50) | HTTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9305296 | 0.78 | PIK3CA (0.50) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1121708 | 0.78 | CYP3A4 (0.57) | HTTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18982832 | 0.78 | NPC1 (0.43) | HTTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2707360 | 0.76 | HDAC6 (0.68) | PIK3CAPIK3CBPIK3CGPI4KBHDAC6 | |
| SCHEMBL14504404 | 0.76 | RAB9A (0.51) | HTTKDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448500-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114822-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |