Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165599 | 1.00 | NAMPT (0.47) | NAMPTKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL1092502 | 0.80 | KDM4E (0.62) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL30220531 | 0.79 | MCL1 (0.60) | NAMPTKDM4ESMN1; SMN2IDO1MAPT | |
| SCHEMBL1569013 | 0.79 | MCL1 (0.60) | NAMPTKDM4ESMN1; SMN2IDO1MAPT | |
| SCHEMBL29900579 | 0.79 | NOD2 (0.44) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL978413 | 0.79 | NOD2 (0.44) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL6796925 | 0.77 | CA12 (0.49) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL4913934 | 0.77 | MEN1 (0.49) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL20951622 | 0.77 | QRFPR (0.44) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL22346624 | 0.77 | QRFPR (0.45) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408845-A1 | NOVEL COMPOUNDS | Sitryx Therapeutics Limited (GB) | 2024-08-07 | — | — | EP | disclosed |
| CN-118139864-A | New compounds | 西特瑞治疗有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023052783-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-04-06 | — | — | WO | disclosed |