Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 19/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.61 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.61 |
| ▸ | CDK9 | P50750 | 3/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390430 | 0.82 | CDK2 (0.73) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL3559853 | 0.79 | CDK2 (0.55) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL5867649 | 0.78 | CCNA2 (0.59) | CDK2CCNA2CCNA1 | |
| SCHEMBL5867732 | 0.78 | CCNA2 (0.62) | CDK2CCNA2CCNA1 | |
| SCHEMBL29659569 | 0.77 | CDK2 (0.79) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL29659491 | 0.77 | CCNA2 (0.70) | CDK2CCNA2CCNA1 | |
| SCHEMBL5868029 | 0.76 | CCNA2 (1.00) | CDK2CCNA2CCNA1 | |
| SCHEMBL3567395 | 0.76 | CDK2 (0.53) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL25649664 | 0.76 | CDK2 (0.78) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL26549015 | 0.76 | IGF1R (0.52) | CDK2CCNA2CCNA1CDK9CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |