Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.53 |
| ▸ | SCD | O00767 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570427 | 1.00 | NOTUM (0.53) | NOTUMSCDAURKAHTR1ASLC6A2 | |
| SCHEMBL20571363 | 0.81 | SCD (0.52) | NOTUMSCD | |
| SCHEMBL30458118 | 0.77 | GPR119 (0.51) | NOTUMSCD | |
| SCHEMBL21821099 | 0.77 | GPR119 (0.51) | NOTUMSCD | |
| SCHEMBL20571413 | 0.75 | NOTUM (0.47) | NOTUMSCDSOS1 | |
| SCHEMBL83377 | 0.74 | HRH1 (0.57) | SCDHTR1ASLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL473008 | 0.73 | HRH1 (0.55) | SCDHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL31071563 | 0.72 | SLC6A2 (0.48) | HTR1ASLC6A2SLC6A3SLC6A4HTR2C | |
| SCHEMBL4262441 | 0.68 | SCD (0.65) | SCD | |
| Trifluoroacetic Acid SCHEMBL69823 | 0.67 | HRH1 (0.51) | SCDHTR1ASLC6A2SLC6A3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |