Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18162478 | 0.90 | MAPT (0.60) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL18153292 | 0.86 | EGFR (0.58) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL3759875 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL904444 | 0.77 | NPC1 (0.60) | MEN1KMT2ARAB9AKDM4EHPGD | |
| SCHEMBL29408382 | 0.77 | NPC1 (0.60) | MEN1KMT2ARAB9AKDM4EHPGD | |
| SCHEMBL12431347 | 0.77 | NCF1 (0.58) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL29110579 | 0.75 | XPO1 (0.52) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL108881 | 0.74 | HPGD (0.78) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL9516537 | 0.74 | HPGD (0.78) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL50079 | 0.74 | HPGD (0.78) | MAPTMEN1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010150166-A | METHOD FOR PRODUCING AZACALIX [3] PYRIDINE COMPOUNDS | TOSOH CORP | 2010-07-08 | — | — | JP | disclosed |