Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 14/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938336 | 1.00 | KMO (0.70) | KMOSLC6A3CNR2SLC6A2JAK2 | |
| SCHEMBL25263065 | 0.95 | KMO (0.64) | KMOSLC6A3CNR2SLC6A2JAK2 | |
| SCHEMBL25224968 | 0.95 | KMO (0.80) | KMO | |
| SCHEMBL1938367 | 0.85 | KMO (0.67) | KMO | |
| SCHEMBL1938479 | 0.84 | KMO (0.72) | KMOJAK2JAK3 | |
| SCHEMBL14742247 | 0.84 | KMO (0.76) | KMO | |
| SCHEMBL1938372 | 0.84 | KMO (0.68) | KMO | |
| SCHEMBL1939271 | 0.83 | KMO (0.70) | KMOCNR2 | |
| SCHEMBL1937823 | 0.83 | SMN1; SMN2 (0.56) | KMO | |
| SCHEMBL1938969 | 0.83 | KMO (0.70) | KMOJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323583-A | Heterobiaryl compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-06-23 | — | — | CN | disclosed |