Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30459469

COC(=O)c1ccc2cccc(F)c2n1.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.43
MAPT P10636 3/20 0.42
KDM4E B2RXH2 1/20 0.40
KMT2A Q03164 1/20 0.40
PTGER4 P35408 1/20 0.40
CYSLTR2 Q9NS75 1/20 0.39
CYSLTR1 Q9Y271 1/20 0.39
MMP2 P08253 1/20 0.39
TACR3 P29371 1/20 0.38
CYP1A2 P05177 2/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29087787 0.92 MAPT (0.48) ADORA2AMAPTKDM4EKMT2APTGER4
Trifluoroacetic Acid SCHEMBL28462831 0.79 MGAM (0.54) MAPTKDM4EKMT2AGAARAB9A
SCHEMBL2950729 0.77 ALDH1A1 (0.44) MAPTKDM4EKMT2APTGER4CYP1A2
SCHEMBL4751890 0.76 KDM4E (0.66) KDM4EKMT2AMMP2
SCHEMBL31385428 0.76 KDM4E (0.66) KDM4EKMT2AMMP2
SCHEMBL4995737 0.75 MAPK1 (0.50) MAPTKDM4EKMT2APTGER4CYP1A2
SCHEMBL2118060 0.75 CA1 (0.45) MAPTKDM4EKMT2APTGER4MMP2
SCHEMBL23714070 0.75 CYP1A2 (0.47) MAPTKDM4EKMT2APTGER4MMP2
SCHEMBL847651 0.75 KDM4E (0.65) MAPTKDM4EKMT2APTGER4CYP1A2
SCHEMBL31429914 0.75 KDM4E (0.48) MAPTKDM4EKMT2APTGER4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493453-B Condensed aromatic ring derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2023-06-16 CN disclosed