Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17683072 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL8647486 | 0.85 | TDP1 (0.43) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL10334256 | 0.81 | TDP1 (0.43) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL23389142 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TDP1ATMHIF1ATSHR | |
| SCHEMBL30068485 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TDP1ATMHIF1ATSHR | |
| SCHEMBL20987127 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL32671770 | 0.80 | HTT (0.53) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL2924231 | 0.80 | HTT (0.53) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL30568356 | 0.80 | TDP1 (0.42) | ALDH1A1TDP1ATMHIF1AVCAM1 | |
| SCHEMBL28203549 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402143-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117069700-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111187221-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-111171000-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-111170999-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |