Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17683153 | 1.00 | ADORA2A (0.50) | ADORA2AADORA2BKDM4EALDH1A1HPGD | |
| SCHEMBL11708958 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| Hydrochloric Acid SCHEMBL11708649 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL16867222 | 0.78 | ADORA2A (0.67) | ADORA2AADORA2BAURKACDK4CCNA2 | |
| SCHEMBL11546262 | 0.77 | PDE4A (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2PDE3A | |
| SCHEMBL14297421 | 0.76 | ADORA2A (0.59) | ADORA2AADORA2BKDM4EALDH1A1HPGD | |
| SCHEMBL27927364 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2PDE3A | |
| SCHEMBL11750245 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2PDE3A | |
| SCHEMBL15540970 | 0.74 | NTRK1 (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2PDE3A | |
| SCHEMBL28141790 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402143-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117069700-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111187221-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-111171000-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-111170999-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |