Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
| ▸ | INPP5B | P32019 | 1/20 | 0.34 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637102 | 0.81 | NPSR1 (0.42) | SRCACP3MAPTL3MBTL1CYP1A2 | |
| SCHEMBL9450849 | 0.68 | PGK1 (0.33) | SRCACP3CYP2C19 | |
| SCHEMBL2953510 | 0.66 | GAA (0.59) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL9450751 | 0.65 | SRC (0.45) | GAASRCACP3KMT2A | |
| SCHEMBL18287898 | 0.65 | MGAM (0.61) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL16970568 | 0.65 | INPPL1 (0.39) | GAASRCMAPTINPPL1INPP5B | |
| SCHEMBL3045991 | 0.65 | PGK1 (0.52) | L3MBTL1 | |
| SCHEMBL31060482 | 0.64 | CA1 (0.44) | SRCACP3L3MBTL1KMT2ANPSR1 | |
| SCHEMBL27894557 | 0.64 | MAPT (0.66) | MAPTL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9450742 | 0.64 | SRC (0.61) | SRCACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221180-A1 | IN VIVO IMAGING OF MYELINATION | WANG YANMING | 2010-09-02 | — | — | US | disclosed |
| EP-2198040-A1 | IN VIVO IMAGING OF MYELIN | Case Western Reserve University (US) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009029936-A1 | IN VIVO IMAGING OF MYELIN | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221180-A1 | IN VIVO IMAGING OF MYELINATION | MAG, PMP22, MYT1 | MGAM 3602/4885GAA 4568/4885SI 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.