Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 5/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723054 | 0.85 | BPTF (0.62) | BPTFHRH4KDM4ECYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL21274572 | 0.83 | BPTF (0.61) | BPTFHRH4KDM4ECYP3A4HSD17B10 | |
| Tert-Butyl Formate SCHEMBL25272391 | 0.81 | BPTF (0.46) | BPTFHRH4KDM4ECYP3A4HSD17B10 | |
| SCHEMBL20255516 | 0.80 | TRPV1 (0.38) | BPTFKDM4EALDH1A1MEN1KMT2A | |
| Pivalate SCHEMBL28600103 | 0.77 | CHRNB2 (0.49) | KDM4EHSD17B10HTR6ALDH1A1KCNH2 | |
| SCHEMBL25272390 | 0.74 | MAP4K4 (0.37) | BPTFKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2421817 | 0.73 | BPTF (0.56) | BPTFKDM4ECYP3A4HSD17B10HTR6 | |
| SCHEMBL1393962 | 0.73 | KDM4E (0.43) | BPTFKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL29942240 | 0.72 | BPTF (0.54) | BPTFKDM4ECYP3A4HSD17B10HRH3 | |
| SCHEMBL24629084 | 0.71 | BPTF (0.47) | BPTFHRH4KDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |