Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30460002 | 0.94 | KDM1A (0.43) | KDM1AIP6K1SIRT2MAPK14OPRM1 | |
| SCHEMBL15129628 | 0.87 | KDM1A (0.39) | KDM1AIP6K1SIRT2MAPK14OPRM1 | |
| SCHEMBL15129836 | 0.87 | KDM1A (0.39) | KDM1AIP6K1SIRT2MAPK14OPRM1 | |
| SCHEMBL16266581 | 0.86 | KDM1A (0.38) | KDM1AIP6K1SIRT2MAPK14OPRM1 | |
| SCHEMBL31390939 | 0.85 | MAPK14 (0.43) | KDM1AIP6K1SIRT2MAPK14OPRM1 | |
| SCHEMBL17444524 | 0.83 | KDM1A (0.43) | KDM1AIP6K1SIRT2MAPK14TSHR | |
| SCHEMBL29041923 | 0.82 | MAP4K1 (0.35) | MAP4K1KCNH2HDAC1RARARARB | |
| SCHEMBL29930072 | 0.82 | KDM4E (0.44) | KDM1AIP6K1RARARARBRARG | |
| SCHEMBL22058140 | 0.78 | KDM1A (0.40) | KDM1AIP6K1SIRT2MAPK14OPRM1 | |
| SCHEMBL29930324 | 0.77 | LMNA (0.41) | IP6K1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457346-A | Preparation of indolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-07-18 | — | — | CN | disclosed |