Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 9/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25351277 | 1.00 | HDAC6 (0.46) | HDAC6PDE4DKDM1AADORA2ATUBB4A | |
| SCHEMBL30460211 | 0.90 | HDAC6 (0.47) | HDAC6PDE4DKDM1AADORA2AP2RY14 | |
| SCHEMBL30460216 | 0.90 | HDAC1 (0.43) | HDAC6PDE4DKDM1AADORA2AKDM1B | |
| SCHEMBL25351650 | 0.90 | HDAC6 (0.47) | HDAC6PDE4DKDM1AADORA2AP2RY14 | |
| SCHEMBL25348693 | 0.90 | HDAC1 (0.43) | HDAC6PDE4DKDM1AADORA2AKDM1B | |
| SCHEMBL25351332 | 0.89 | HDAC6 (0.46) | HDAC6KDM1ATUBB4ATUBBTUBA3C | |
| SCHEMBL30460213 | 0.89 | HDAC6 (0.46) | HDAC6KDM1ATUBB4ATUBBTUBA3C | |
| SCHEMBL25347853 | 0.88 | HDAC6 (0.43) | HDAC6KDM1ATUBB4ATUBBTUBA3C | |
| SCHEMBL25351106 | 0.88 | HDAC6 (0.48) | HDAC6NAMPTKDRTEK | |
| SCHEMBL30460243 | 0.88 | HDAC6 (0.48) | HDAC6NAMPTKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |