Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | TEK | Q02763 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25351106 | 1.00 | HDAC6 (0.48) | HDAC6HDAC1NAMPTALOX15HSD17B10 | |
| SCHEMBL25351613 | 0.89 | HDAC6 (0.47) | HDAC6HDAC1MAPT | |
| SCHEMBL30460299 | 0.89 | HDAC1 (0.54) | HDAC6HDAC1 | |
| SCHEMBL24215983 | 0.89 | HDAC1 (0.54) | HDAC6HDAC1 | |
| SCHEMBL25351277 | 0.88 | HDAC6 (0.46) | HDAC6NAMPTKDRTEK | |
| SCHEMBL30460238 | 0.88 | HDAC6 (0.46) | HDAC6NAMPTKDRTEK | |
| SCHEMBL24216687 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1KMT2AKDRTEK | |
| SCHEMBL30409410 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1KMT2AKDRTEK | |
| SCHEMBL31535166 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1NAMPTKDRTEK | |
| SCHEMBL24216393 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1NAMPTKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |