Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | PRNP | P04156 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | NR0B1 | P51843 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brefeldin A SCHEMBL4967925 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL17167480 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL30460466 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL12648486 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL29268 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL13073124 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL4967944 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL4345242 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL8264765 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL26040278 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773287-B | Bioactive secondary metabolite and preparation and application thereof | 中国科学院沈阳应用生态研究所 | 2023-06-16 | — | — | CN | disclosed |