Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895465 | 0.88 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL3050394 | 0.86 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL8908352 | 0.81 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL19203449 | 0.78 | KMT2A (0.56) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL27783385 | 0.78 | KMT2A (0.56) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL8895105 | 0.75 | MEN1 (0.37) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL8894670 | 0.74 | MEN1 (0.40) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL3054171 | 0.74 | KMT2A (0.57) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL40674 | 0.74 | KMT2A (0.57) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL7144646 | 0.74 | KMT2A (0.57) | MEN1KMT2AALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772190-B2 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | BAYER ANIMAL HEALTH GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-20040034048-A1 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
| US-20020142969-A1 | DIDEPSIPEPTIDE-BASED ENDOPARASITICIDES, NEW DIDEPSIPEPTIDES AND PROCESS FOR PREPARING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034048-A1 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | VIP, NGLY1, NPEPPS | MEN1 1220/4885KMT2A 4667/4885ALDH1A1 4873/4885 |
| US-20020142969-A1 | DIDEPSIPEPTIDE-BASED ENDOPARASITICIDES, NEW DIDEPSIPEPTIDES AND PROCESS FOR PREPARING THE SAME | VIP, NGLY1, NPEPPS | MEN1 1152/4885KMT2A 4668/4885ALDH1A1 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.